Even when compared to collagen-based fillers like CosmoPlast, Radiesse provided superior results, even after 6 months. The FDA Pivotal trial -- the study that was the basis of the FDA granting approval for the use of Radiesse in the correction of moderate to severe wrinkles and folds of the face, such as Nasolabial Folds – compared Radiesse to CosmoPlast in a split-face multi-site study. At all time points, Radiesse demonstrated clear superiority.
